| Antidotes (Generic Name & Trade Names) |
Poisoning or Overdose Indications | Recommended Stocking Level |
|---|---|---|
| Acetylcysteine (MucomystTM, AcetadoteTM) | Acetaminophen toxicity | 20% oral solution-7 x 30mL; 20% IV solution-4 x 30mL |
| Antivenom (Latrodectus mactans) | Black widow spider envenomation | 1 vial |
| Atropine | Bradydysrhythmias, cholinesterase inhibitor toxicity | 1g |
| Benztropine (CogentinTM) | Acute dystonia | 3 x 2mL, 1mg/mL |
| Botulinum antitoxin / trivalent ABE | Botulism | Available from CDC |
| Calcium disodium EDTA (VersenateTM) | Lead, copper, zinc, cobalt, cadmium toxicity | 18 x 5mL, 200mg/mL |
| Calcium gluconate 10% | Hydrofluoric acid exposure, calcium channel blocker toxicity | 20 -30 vials, 1 gram each |
| Crotalinae polyvalent immune FAB (CroFabTM) | Crotalinae (rattlesnake) envenomation | 10-20 vials |
| Cyproheptadine (PeriactinTM) | Serotonin syndrome | 32mg (4mg tablets or 2mg/5mL syrup) |
| Dantrolene (DantriumTM) | Malignant hyperthermia, neuroleptic malignant syndrome | 35 x 20mg vials |
| Deferoxamine mesylate (DesferalTM) | Iron toxicity | 12x 500mg vials |
| Diazepam / lorazepam (ValiumTM / AtivanTM) | Seizures, severe agitation; stimulant toxicity | 20mg parenteral formulation |
| Digoxin-specific antibody fragments (DigifabTM, DigibindTM) | Digoxin and other cardiac glycoside toxicity | 15-20 vials |
| Dimercaprol / BAL | Arsenic, lead, mercury toxicity | 6 x 3mL, 100mg/mL |
| Diphenhydramine (BenadrylTM) | Acute dystonia; histamine receptor blockade | 8 x 1mL, 50mg/mL |
| Flumazenil (RomaziconTM) | Benzodiazepine toxicity | 10 x 10mL, 0.1mg/mL |
| Folic acid (FolviteTM) | Methanol toxicity | 6 x 10mL, 5mg/mL |
| Fomepizole (AntizolTM) | Ethylene glycol, methanol toxicity | 4 x 1.5mL, 1g/mL |
| Glucagon | Beta-blocker, calcium channel blocker toxicity | 100mg (100 kits, 1unit each) |
| Hydroxocobalamin (CyanokitTM) | Cyanide exposure / smoke inhalation | 15g (3 kits) |
| Leucovorin calcium | Methotrexate toxicity | 2 x 10mL, 10mg/mL |
| Levocarnitine (CarnitorTM) | Valproic acid toxicity | 7 x 5mL, 1g/5mL |
| Levoleucovorin calcium | Methotrexate toxicity | 1 x 50mg vial |
| Methylene blue 1% | Methemoglobinemia | 5x 10mL, 10mg/mL |
| Naloxone (NarcanTM) | Opioid toxicity | 3 x 10mL, 1mg/mL |
| Octreotide (SandostatinTM) | Sulfonylurea toxicity | 2 x 1mL, 0.1mg/mL |
| Physostigmine (AntiliriumTM) | Anticholinergic toxicity | 10 x 2mL, 1mg/mL |
| Phytonadione / Vitamin K1 (AquaMEPHYTONTM / MephytonTM) | Oral anticoagulant / rodenticide toxicicty | 10 x 1mL, 10mg/mL; 20 x 5mg tablets |
| Pralidoxime / 2-PAM (ProtopamTM) | Cholinesterase inhibitor (organophosphate / carbamate) toxicity | 12 x 1g vials |
| Protamine | Heparin reversal | 1 x 25mL, 10mg/mL |
| Pyridoxine / Vitamin B6 | Ethylene glycol / isoniazid / Gyromitra mushroom toxicity | 7 x 30mL, 100mg/mL |
| Sodium bicarbonate | Cyclic antidepressant / salicylate toxicity, metabolic acidosis | 10 amps or syringes (~500mEq) |
| Succimer / DMSA (ChemetTM) | Arsenic, lead, mercury | 21 x 100mg capsules |
| Thiamine / Vitamin B1 | Wernicke-Korsakoff syndrome, ethylene glycol toxicity | 5 x 2mL, 100mg/mL |
1 Recommended stocking amounts should provide a 24-hour supply to treat a severly poisoned 70-kg patient. Institutional needs may vary.